Jean-Philippe Annereau Selected Research

F14512

1/2016	F14512, a polyamine-vectorized inhibitor of topoisomerase II, exhibits a marked anti-tumor activity in ovarian cancer.
12/2011	Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II.
12/2008	F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.

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Jean-Philippe Annereau Research Topics

Disease

10	Neoplasms (Cancer) 01/2016 - 06/2003
2	Melanoma (Melanoma, Malignant) 02/2013 - 04/2005
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2011 - 10/2009
1	Kidney Diseases (Kidney Disease) 01/2023
1	Agenesis of Cerebellar Vermis 01/2023
1	Senior Loken Syndrome 01/2023
1	Ciliopathies 01/2022
1	Ovarian Neoplasms (Ovarian Cancer) 01/2016
1	Ovarian Epithelial Carcinoma 01/2016
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2009
1	Lung Neoplasms (Lung Cancer) 06/2009
1	Neuroblastoma 06/2009
1	Glioblastoma (Glioblastoma Multiforme) 06/2009
1	Rhabdomyosarcoma 06/2009
1	B-Cell Lymphoma (Lymphoma, B Cell) 06/2009
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 06/2009
1	Breast Neoplasms (Breast Cancer) 12/2008
1	Leukemia L1210 12/2008
1	Colonic Neoplasms (Colon Cancer) 08/2008
1	Carcinoma (Carcinomatosis) 11/2005

Drug/Important Bio-Agent (IBA)

3	Type II DNA Topoisomerases (Topoisomerase II)IBA 01/2016 - 12/2008
3	PolyaminesIBA 01/2016 - 12/2008
3	F14512IBA 01/2016 - 12/2008
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 04/2005 - 08/2004
2	Cisplatin (Platino)FDA LinkGeneric 01/2016 - 11/2005
2	Etoposide (VP 16)FDA LinkGeneric 01/2016 - 12/2011
2	SpermineIBA 12/2011 - 12/2008
2	DNA (Deoxyribonucleic Acid)IBA 12/2011 - 12/2008
2	Proteins (Proteins, Gene)FDA Link 06/2009 - 08/2008
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 12/2004 - 06/2003
1	Retinaldehyde (Retinal)IBA 01/2023
1	Dinoprostone (PGE2)FDA Link 01/2022
1	PlatinumIBA 01/2016
1	Carboplatin (JM8)FDA LinkGeneric 01/2016
1	cryptopleurineIBA 01/2015
1	NestinIBA 02/2013
1	Podophyllotoxin (Condylox)FDA LinkGeneric 12/2011
1	PoisonsIBA 12/2011
1	RNA (Ribonucleic Acid)IBA 10/2009
1	triptolideIBA 10/2009
1	Anaplastic Lymphoma KinaseIBA 06/2009
1	F 91874IBA 06/2009
1	PutrescineIBA 12/2008
1	SpermidineIBA 12/2008
1	Antineoplastic Agents (Antineoplastics)IBA 12/2008
1	LuciferasesIBA 08/2008
1	UbiquitinIBA 08/2008
1	Proteasome Endopeptidase Complex (Proteasome)IBA 08/2008
1	Ether (Diethyl Ether)IBA 11/2005
1	Inwardly Rectifying Potassium Channels (Inward Rectifier Potassium Channels)IBA 11/2005
1	RNA IsoformsIBA 04/2005
1	multidrug resistance-associated protein 1IBA 12/2004
1	Messenger RNA (mRNA)IBA 08/2004

Therapy/Procedure

4	Therapeutics 01/2016 - 04/2005
1	Drug Therapy (Chemotherapy) 08/2004